Issues in quantifying atrophic macular disease using retinal autofluorescence.
To demonstrate the potential and limits of autofluorescence imaging in identifying and delineating areas of atrophy. Read More…
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A list of ProgStar updates, news and publications, as well as publications relevant to STGD by ProgStar study investigators.
For a list of all published ProgStar study reports please click here.
A video of a presentation by HPN Scholl (including ppt slides ) and a summary of the main ProgStar study results may be found here.
To demonstrate the potential and limits of autofluorescence imaging in identifying and delineating areas of atrophy. Read More…
To determine whether adipose and red blood cell membrane lipids, particularly long-chain polyunsaturated fatty acids such as docosahexaenoic acid and eicosapentaenoic acid, are significantly correlated with phenotype in a family with autosomal dominant Stargardt macular dystrophy (gene locus STGD3). Read More…
To study the parapapillary retinal region in patients with ABCA4-associated retinal degenerations. Read More…
MFRP is a member of the frizzled-related protein family and contains a cysteine-rich domain essential for Wnt binding and signaling. MFRP is highly expressed in the retinal pigment epithelial cells of the eye. Read More…
Psychophysical and electroretinographic (ERG) studies indicate that patients with Stargardt disease exhibit abnormally slow rod dark adaptation after illumination that bleaches a substantial fraction of rhodopsin. Read More…
Mutations in ABCA4, which encodes a photoreceptor specific ATP-binding cassette transporter (ABCR), cause autosomal recessive forms of human blindness due to retinal degeneration (RD) including Stargardt disease. The exact disease sequence leading to photoreceptor and vision loss in ABCA4-RD is not known. Read More…
Detail results of Stargardt disease in a patient with retinoblastoma. Read More…
It has been hypothesized that the macular carotenoid pigments lutein and zeaxanthin may protect against macular and retinal degenerations and dystrophies. Read More…
To describe the phenotype of an autosomal dominant macular dystrophy and identify the chromosomal locus. Read More…
To investigate the slow and fast rod signals of the scotopic 15-Hz flicker ERG in patients with molecularly confirmed Stargardt disease type I (STGD1). Read More…